Structure–activity relationship of N-methyl-bisindolylmaleimide derivatives as cell death inhibitors
-
Add time:08/28/2019 Source:sciencedirect.com
A series of N-methyl-bisindolylmaleimide derivatives was synthesized and evaluated as cell death inhibitors. N-Methyl-2-[1-(3-aminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide (21) was the most potent inhibitor of H2O2-induced necrotic death of human leukemia HL60 cells among them.
We also recommend Trading Suppliers and Manufacturers of Bisindolylmaleimide V (cas 113963-68-1). Pls Click Website Link as below: cas 113963-68-1 suppliers
Prev:Identification of bisindolylmaleimides and indolocarbazoles as inhibitors of HCV replication by tube-capture-RT-PCR
Next:Direct block by bisindolylmaleimide of the voltage-dependent K+ currents of rat mesenteric arterial smooth muscle) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220) are potent inhibitors of glycogen synthase kinase-3 activity09/03/2019
- A convenient synthesis of bisindolylmaleimides09/02/2019
- Design and synthesis of AX4697, a bisindolylmaleimide exo-affinity probe that labels protein kinase C alpha and beta09/01/2019
- Chelerythrine and bisindolylmaleimide I prolong cardiac action potentials by protein kinase C-independent mechanism08/31/2019
- Bisindolylmaleimide I and V inhibit necrosis induced by oxidative stress in a variety of cells including neurons08/30/2019
- Direct block by bisindolylmaleimide of the voltage-dependent K+ currents of rat mesenteric arterial smooth muscle08/29/2019
- Identification of bisindolylmaleimides and indolocarbazoles as inhibitors of HCV replication by tube-capture-RT-PCR08/27/2019
- Soluble porphyrin–bisindolylmaleimides dyad and pentamer as saturated red luminescent materials08/26/2019
- Short communicationMuscarinic interactions of bisindolylmaleimide analogues08/25/2019
