Amphiregulin suppresses epithelial cell apoptosis in lipopolysaccharide-induced lung injury in mice
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Add time:08/26/2019 Source:sciencedirect.com
Background and objectiveAs a member of the epidermal growth factor family, amphiregulin contributes to the regulation of cell proliferation. Amphiregulin was reported to be upregulated in damaged lung tissues in patients with chronic obstructive pulmonary disease and asthma and in lung epithelial cells in a ventilator-associated lung injury model. In this study, we investigated the effect of amphiregulin on lipopolysaccharide (LPS)-induced acute lung injury in mice.
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