Penthorin A and B, two unusual 2,4′-epoxy-8,5′-neolignans from Penthorum chinese

Add time:08/26/2019    Source:sciencedirect.com

Two new 2,4′-epoxy-8,5′-neolignans (1 and 2), together with five known 7,9′;7′,9-diepoxylignans (3 − 7), were isolated from an ethyl acetate soluble portion of a hepatoprotective water decoction of Penthorum chinese. Their structures and absolute configurations were elucidated by extensive spectroscopic analyses and electronic circular dichroism (ECD) calculations. This is the second report of 2,4′-epoxy-8,5′-neolignans from plants. Compounds 2, 6, and 7 showed in vitro protective activities against acetaminophen-induced hepatocyte injury at 5 μM.

We also recommend Trading Suppliers and Manufacturers of 8,5'(S)-CYCLO-2'-DEOXYADENOSINE (cas 117182-88-4). Pls Click Website Link as below: cas 117182-88-4 suppliers

Prev:Three new 2,4′-epoxy-8,5′/8,3′-neolignans from Penthorum chinense
Next:Photochemical cyclisation of 2',3'-0-isopropylidene-8-phenylthioadenosine to the 8,5'(R)- and 8,5'(S)-cycloadenosines (nucleosides and nucleoti)