Regioselective ortho-acetoxylation/methoxylation of N-(2-benzoylphenyl)benzamides via substrate directed C–H activation

Add time:08/25/2019    Source:sciencedirect.com

A highly regioselective ortho-acetoxylation of N-(2-benzoylphenyl)benzamides has been achieved using a catalytic amount of Pd(OAc)2 (10 mol %) and a stoichiometric amount of PhI(OAc)2 in a mixture of acetic anhydride and acetic acid via C–H activation to produce the corresponding 2-acetoxybenzamides in good yields. ortho-Methoxylation has been accomplished using methanol under similar conditions.

We also recommend Trading Suppliers and Manufacturers of (S)-N-(2-Benzoylphenyl)-2-pyrrolidinecarboxamide (cas 117186-74-0). Pls Click Website Link as below: cas 117186-74-0 suppliers

Prev:Original articleSynthesis, structure–activity relationships, and in vitro antibacterial and antifungal activity evaluations of novel pyrazole carboxylic and dicarboxylic acid derivatives
Next:N-(2-Benzoylphenyl)benzamido nickel(II) complexes and polymerization reactivity)