An efficient access to (1H-tetrazol-5-yl)furoxan ammonium salts via a two-step dehydration/[3+2]-cycloaddition strategy

Add time:07/14/2019    Source:sciencedirect.com

A general, highly effective two-step approach for direct synthesis of (1H-tetrazol-5-yl)furoxan ammonium salts with various functional substituents based on initial effective synthesis of cyanofuroxans by dehydration of furoxancarboxylic acid amides by the action of (CF3CO)2O/Py followed by [3+2]-cycloaddition of cyanofuroxans to ammonium azide, generated in situ from TMSN3 and NH4F, has been developed.

We also recommend Trading Suppliers and Manufacturers of 2-{[5-(4-methyl-1,2,5-oxadiazol-3-yl)-1H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide (cas 50412-82-3). Pls Click Website Link as below: cas 50412-82-3 suppliers

Prev:Synthesis of novel 1,2,5-oxadiazoles and evaluation of action against Acinetobacter baumannii
Next:Pronounced anti-proliferative activity and tumor cell selectivity of 5-alkyl-2-amino-3-methylcarboxylate thiophenes)