Efficient synthesis of a new pipecolic acid analogue with a bicyclic structure

Add time:07/13/2019    Source:sciencedirect.com

This report describes the synthesis of 2-azabicyclo[2.2.2]octane-1-carboxylic acid, a constrained pipecolic acid analogue. The route gives a very good total yield starting from cheap and readily available compounds and uses very easy reactions.

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