First total synthesis of (−)-VERRUCULOGEN (cas 12771-72-1) tr-2☆
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Add time:08/27/2019 Source:sciencedirect.com
The total synthesis of the tremorgenic mycotoxin Verruculogen TR-2 (6) is presented. Selective oxidation of 1 to yield 3 or 4 was achieved using 2. Compound 4 was elaborated to the title compound employing osmium tetroxide.
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