The solution conformation of 1-(3,5-dimethylphenyl)methyl-3(S)-(1H-indol-3-yl)methyl-6(S)-phenylmethyl-2,5-piperazinedione (1): An NMR and molecular modelling study

Add time:08/29/2019    Source:sciencedirect.com

Comparison of NMR data with structures from molecular modelling of 1-(3,5-dimethylphenyl)methyl-3(S)-(1H-indol-3-yl)methyl-6-(S)-phenylmethyl-2,5-piperazinedione (1) showed it to have a specific solution conformation with the phenyl ring over the diketopiperazine ring and the tryptophan sidechain in the [G−o] rotamer.

We also recommend Trading Suppliers and Manufacturers of 1-(2,5-Dimethylphenyl)-2-buten-1-one (cas 15561-15-6). Pls Click Website Link as below: cas 15561-15-6 suppliers

Prev:Spectroscopic and electrochemical properties of 4-[(4′-hydroxy-3′,5′-dimethylphenyl)(aryl)-methylene]-2,6-dimethylcyclohexa-2,5-dienones
Next:Pd-catalyzed Suzuki/Sonogashira cross-coupling reaction and the direct sp3 arylation of 7-chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine)