Reporter molecules as probes of DNA conformation: Structure of a crystalline complex containing 2-Methyl-4-nitroaniline ethylene dimethylammonium hydrobromide — 5-iodocytidylyl(3′–5′)guanosine

Add time:08/30/2019    Source:sciencedirect.com

2-Methyl-4-nitroaniline ethylene dimethylammonium hydrobromide forms a crystalline complex with the self-complementary dinucleoside monophosphate, 5-iodocytidylyl(3′–5′)guanosine. The crystals are tetragonal, with a = b = 32.192 Å and c = 23.964 Å, space group P43212. The structure has been solved to atomic resolution by Patterson and Fourier methods, and refined by full matrix least squares. 5-Iodocytidylyl(3′–5′)guanosine molecules are held together in pairs through Watson-Crick base-pairing, forming an antiparallel duplex structure. Nitroaniline molecules stack above and below guanine-cytosine pairs in this duplex structure. In addition, a third nitroaniline molecule stacks on one of the other two nitroaniline molecules. The asymmetric unit contains two 5-iodocytidylyl(3′–5′)guanosine molecules, three nitroaniline molecules, one bromide ion and thirty-one water molecules, a total of 160 atoms. Details of the structure are described.

We also recommend Trading Suppliers and Manufacturers of 4-Methyl-3-nitroaniline (cas 119-32-4). Pls Click Website Link as below: cas 119-32-4 suppliers

Prev:Conformational studies of N-(α-d-glucofuranurono-6,3-lactone)- and N-(methyl β-d-glucopyranuronate)-p-nitroanilines
Next:Syntheses, characterizations, crystal structures and efficient NLO applications of new organic compounds bearing 2-methoxy-4-nitrobenzeneamine moiety and copper (II) complex of (E)-N'-(3, 5-dichloro-2-hydroxybenzylidene) benzohydrazide)