Easy access to synthesize Isoquinoline (cas 119-65-3)s from aryl ketoximes and internal alkynes via Iridium (III)-catalyzed CH/NO bond activation
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Add time:09/01/2019 Source:sciencedirect.com
A highly efficient approach to synthesize isoquinoline derivatives through Iridium(III)-catalyzed cyclization of aryl ketoximes and internal alkynes without oxidant is reported. A broad range isoquinolines are obtained in good to excellent yields and various functional groups are well tolerated.
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