Research paperMicroRNA-24 regulates vascular remodeling via inhibiting PDGF-BB pathway in diabetic rat model

Add time:09/02/2019    Source:sciencedirect.com

PurposeHyperglycemia is the high risk factor of vascular remodeling induced by angioplasty, and neointimal hyperplasia is strongly implicated in the pathogenesis of vascular remodeling caused by carotid artery balloon injury. Studies have shown that MicroRNA 24 (miR-24) plays an important role in angiocardiopathy, However, the role of miR-24 is far from thorough research. In this study, we investigate whether up-regulation of miR-24 by using miR-24 recombinant adenovirus (Ad-miR-24-GFP) can inhibit PDGF-BB signaling pathway and attenuate vascular remodeling in the diabetic rat model.

We also recommend Trading Suppliers and Manufacturers of Fast Blue BB (cas 120-00-3). Pls Click Website Link as below: cas 120-00-3 suppliers

Prev:Effects of TGFβ1, PDGF-BB, and bFGF, on human corneal fibroblasts proliferation and differentiation during stromal repair☆
Next:Controlled delivery of platelet-derived growth factor-BB from injectable microsphere/hydrogel composites)