A miniature electrochemical detection system based on GOQDs/MWCNTs /SPCE* for determination the Purine (cas 120-73-0) in cells
-
Add time:09/02/2019 Source:sciencedirect.com
The development of a simple, portable and accurate instrument used in the evaluation of in vitro cytotoxicity is particularly important and urgent in the field of toxicology research at present. In the current study, a miniature electrochemical detection system was constructed that integrated graphene oxide quantum dots and multiwall carbon nanotubes modified anodized screen printed carbon electrode (GOQDs/MWCNTs/SPCE*) with a mini reaction vessel, which reduced the consumption of sample from 500 to 80 μL. Four electrochemical signals could be detected in cells distinctly for the first time which were attributed to the oxidation of uric acid, guanine/xanthine, adenine and hypoxanthine, respectively. This miniature electrochemical detection system has better selectivity, sensitivity and its detection limits were lower than those of most electrochemical sensors. Furthermore it has been found that the level of Purine (cas 120-73-0) nucleotide metabolism in BALB/3T3 cells and MCF-7 cells was different, which could be related to the different purine nucleotide metabolisms of cancer cells and non cancer cells. The simple, portable and miniature electrochemical detection system could be used as a convenient instrument for toxicology detection.
We also recommend Trading Suppliers and Manufacturers of Purine (cas 120-73-0). Pls Click Website Link as below: cas 120-73-0 suppliers
Prev:Effects of breeds, tissues and genders on Purine (cas 120-73-0) contents in pork and the relationships between Purine (cas 120-73-0) content and other meat quality traits
Next:PFOA and PFOS promote diabetic renal injury in vitro by impairing the metabolisms of amino acids and Purine (cas 120-73-0)s) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- 6-Substituted Purine (cas 120-73-0)s as ROCK inhibitors with anti-metastatic activity09/04/2019
- PFOA and PFOS promote diabetic renal injury in vitro by impairing the metabolisms of amino acids and Purine (cas 120-73-0)s09/03/2019
- Effects of breeds, tissues and genders on Purine (cas 120-73-0) contents in pork and the relationships between Purine (cas 120-73-0) content and other meat quality traits09/01/2019
- Dynamic compartmentalization of Purine (cas 120-73-0) nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma08/31/2019
- ReviewPurine (cas 120-73-0) salvage in plants08/30/2019
- Label-free electrochemical analysis of Purine (cas 120-73-0) nucleotides and nucleobases at disposable carbon electrodes in microliter volumes08/29/2019
- Aromaticity of the most stable adenine and Purine (cas 120-73-0) tautomers in terms of Hückel's 4N+2 principle08/28/2019