K2S2O8-Mediated halogenation of 2-arylimidazo[1,2-a]pyridines using sodium halides as the halogen sources
-
Add time:08/28/2019 Source:sciencedirect.com
A convenient halogenation of 2-arylimidazo[1,2-a]pyridines using sodium chloride/bromide/iodide as the halogen sources in the presence of K2S2O8 as an easy-to-handle oxidizing agent was developed. The present work offers an efficient and rapid access to 3-chloro-, 3-bromo- and 3-iodo-2-arylimidazo[1,2-a]pyridines which can be readily converted to C3-substituted imidazo[1,2-a]pyridines by cross-coupling reactions.
We also recommend Trading Suppliers and Manufacturers of 8-Bromo-6-methylimidazo[1,2-a]pyridine (cas 136117-93-6). Pls Click Website Link as below: cas 136117-93-6 suppliers
Prev:IPD-196, a novel phosphatidylinositol 3-kinase inhibitor with potent anticancer activity against hepatocellular carcinoma
Next:NBS mediated one-pot regioselective synthesis of 2,3-disubstituted imidazo[1,2-a]pyridines and their unambiguous characterization through 2D NMR and X-ray crystallography) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Design, synthesis and biological evaluation of 7-methylimidazo[1,5-a]pyrazin-8(7H)-one derivatives as BRD4 inhibitors08/31/2019
- Nickel-catalyzed C(sp2)-H selenation of imidazo[1,2-α]pyridines with arylboronic acids or alkyl reagents using selenium powder08/30/2019
- NBS mediated one-pot regioselective synthesis of 2,3-disubstituted imidazo[1,2-a]pyridines and their unambiguous characterization through 2D NMR and X-ray crystallography08/29/2019
