An efficient synthesis of 5-aminoimidazol-2-ones via cyclization reactions of 2-aminoacetonitriles and isocyanates
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Add time:09/01/2019 Source:sciencedirect.com
The scope of a cyclization reaction between amino-acetonitriles and isocyanates was investigated. The study revealed that this reaction tolerates various functional groups leading to highly functionalized 5-amino-imidazole-2-ones, which are useful intermediates for purine synthesis.
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