Introduction of the 4,4′4′-tris(benzoyloxy)trityl group into the exo amino groups of deoxyribonucleosides and its properties
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Add time:09/04/2019 Source:sciencedirect.com
The 4,4′,4′-tris(benzoyloxy)trityl (TBTr) group was introduced into the amino groups of the common deoxyribonucleosides by means of the transient protection using the trimethylsilyl group. The TBTr group introduced onto the N6 -amino group of deoxyadenosine was found to have considerable retarding effects on the depurination when treated with acids.
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