Boron tribromide mediated debenzylation of benzylamino and benzyloxy groups
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Add time:09/02/2019 Source:sciencedirect.com
The treatment of 2(or 4)-benzylamino substituted quinolines, 9-benzylaminoacridine, 2-benzylaminopyridine, a 4-benzyloxyquinoline, and an N-benzyloxyamidine with BBr3 yields the corresponding amino or hydroxy substituted compounds. The scope and limitations of this novel reaction are discussed.
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