Enzymatic ammonolysis of ethyl (±)-4-chloro-3-hydroxybutanoate. Chemoenzymatic syntheses of both enantiomers of pyrrolidin-3-ol and 5-(chloromethyl)-1,3-oxazolidin-2-one
-
Add time:07/14/2019 Source:sciencedirect.com
Lipase B from Candida antarctica efficiently catalysed the kinetic resolution of ethyl (±)-4-chloro-3-hydroxybutanoate through an ammonolysis reaction. Using this methodology, both enantiomers of 4-chloro-3-hydroxybutanamide were prepared and converted into pyrrolidin-3-ol and 5-(chloromethyl)-1,3-oxazolidin-2-one by simple processes consisting of a reduction reaction and a Hofmann rearrangement, respectively.
We also recommend Trading Suppliers and Manufacturers of 5-CHLORO-4-(CHLOROMETHYL)-1-METHYL-3-PHENYL-1H-PYRAZOLE (cas 321538-19-6). Pls Click Website Link as below: cas 321538-19-6 suppliers
Prev:ELTA: Enzymatic Labeling of Terminal ADP-Ribose
Next:Kinetics and mechanism of the reactions of chloromethyl radical with acetylene and decomposition of 1-chloroallyl and 2-chloromethyl vinyl radicals) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Alkylation versus trans-silylation of N-methyl-N-trimethylsilylacetamide with ambident electrophiles (chloromethyl)fluorosilanes07/17/2019
- Salmonella and mammalian-cell mutagenicity of 3-chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone07/16/2019
- Kinetics and mechanism of the reactions of chloromethyl radical with acetylene and decomposition of 1-chloroallyl and 2-chloromethyl vinyl radicals07/15/2019
