Radical anions of nitrosoimidazoles: Putative intermediates in the mechanism of action of nitroimidazole antibiotics

Add time:08/31/2019    Source:sciencedirect.com

The radical anions of 1-methyl-4-phenyl-5-nitrosoimidazole and 5-phenyl-4-nitrosoimidazole have been detected using temperature resolved e.s.r, spectroscopic techniques and are proposed as putative intermediates in the oxidation of thiols to disulphides by the nitrosoimidazoles.

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