The solubilities of modified hemoglobins
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Add time:09/03/2019 Source:sciencedirect.com
1.1. Hemoglobin A was modified with many reducing sugars and with acetylsalicylate.2.2. The solubilities of the glycosylated hemoglobins were substantially higher than the unmodified control both in oxygenated and m deoxygenated conformations.3.3. A slight decrease in solubility was observed for the acetylated hemoglobin.4.4. With deoxyhemoglobin S increases in solubility were found for each of these modifiers, but the reducing monosaccharides seemed to be the better anti-sickling agents.
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