Simple stepwise route to 1-substituted 2-amino-3-ethoxycarbonylindolizines
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Add time:07/18/2019 Source:sciencedirect.com
2-Chloro-N-ethoxycarbonylmethylpyridinium bromide reacts with substituted acetonitriles in two steps; the initially formed pyridine anhydro baseses undergo further ring closure to 2-amino-3-ethoxycarbonylindolizines.
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