Synthesis and cvs activity of 1-(2,3, 2,5, 2,6 Dichlorophenyl)-3-MorpholinophenyL-5-Substituted benzylidine-thiobarbituric acids (3–17)
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Add time:07/19/2019 Source:sciencedirect.com
Fifteen new thiobarbituric acids have been prepared by the Knoevenagel condensation of appropriate aldehydes with 1-(2,3, 2,5, 2,6 dichlorophenyl)-3-morpholinophenyl thiobarbituric acids. Five compounds of this series were found to be biphasic in nature whereas some compounds showed appreciable hypotensive activity of varying magnitude and duration.
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