Facile p-toluenesulfonic acid-promoted para-selective monobromination and chlorination of phenol and analogues

Add time:08/31/2019    Source:sciencedirect.com

para-Regioselective bromination of phenol and analogues, promoted by p-toluenesulfonic acid, is achieved in high to excellent yields at room temperature with N-bromosuccinimide. Chlorination with N-chlorosuccinimide and catalysed by p-toluenesulfonic acid also gives para-chlorinated phenol analogues in good yields at room temperature.

We also recommend Trading Suppliers and Manufacturers of 2-PYRIDINESULFONIC ACID METHYL ESTER (cas 111480-82-1). Pls Click Website Link as below: cas 111480-82-1 suppliers

Prev:An enantiodivergent synthesis of Cα-methyl nipecotic acid analogues from δ-lactam derivatives obtained through a highly stereoselective cyclization strategy
Next:FTIR study on deactivation of sulfonyl chloride functionalized ionic materials as dual catalysts and media for Beckmann rearrangement of cyclohexanone oxime)