2′-Amino-2′-deoxy-N6-(1-naphthylmethyl)adenosine as Novel Scaffold for a Polymer-Assisted Amidation Protocol

Add time:07/15/2019    Source:sciencedirect.com

The synthesis of a novel scaffold for the simple and high-yielding polymer-assisted solution phase preparation of arrays of 2′-amido-2′-deoxy-N6-(1-naphthylmethyl)adenosine derivatives 10a–h as analogues of a known inhibitor of trypanosomatid glycosomal glyceraldehyde-3-phosphate dehydrogenase is described.

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