A process for the rapid removal of dialkylamino-substituents from aromatic rings. Application to the expedient synthesis of (R)-tolterodine
-
Add time:09/02/2019 Source:sciencedirect.com
A range of N,N-dialkylanilines have been successfully converted to the parent substituted benzenes by a novel two-step pathway. The products are obtained in good yields and optical purity of adjacent stereocenters is maintained. This technology has been applied toward the synthesis of (R)-tolterodine.
We also recommend Trading Suppliers and Manufacturers of bis[(R)-[cyano(phenyl)methyl]ammonium] [R-(R*,R*)]-tartrate (cas 19720-18-4). Pls Click Website Link as below: cas 19720-18-4 suppliers
Prev:Dose-limiting inhibition of acetylcholinesterase by ladostigil results from the rapid formation and fast hydrolysis of the drug–enzyme complex formed by its major metabolite, R-MCPAI
Next:Short communicationIsolation, identification and characterization of degradant impurities in Tolterodine tartrate formulation) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- A new approach to enantiomerically pure bis-imidazoles derived from trans-1,2-diaminocyclohexane09/04/2019
- Short communicationIsolation, identification and characterization of degradant impurities in Tolterodine tartrate formulation09/03/2019
- Dose-limiting inhibition of acetylcholinesterase by ladostigil results from the rapid formation and fast hydrolysis of the drug–enzyme complex formed by its major metabolite, R-MCPAI09/01/2019
- An efficient enantioselective synthesis of (R,R)-formoterol, a potent bronchodilator, using lipases08/31/2019
