A facile synthesis of 3-(substituted benzyl)piperidines
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Add time:08/31/2019 Source:sciencedirect.com
A convenient new method has been developed for preparation a series of 3-(substituted benzyl)piperidines by addition of substituted phenylmagnesium bromide to pyridine-3-carboxaldehyde followed by one pot deoxygenation and heteroaromatic ring saturation in the presence of palladium catalyst.
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