Diastereoselective fluorination of chiral imide enolates using N-FLUORO-O-BENZENEDISULFONIMIDE (cas 1344-80-5) (nfobs)

Add time:09/01/2019    Source:sciencedirect.com

α-Fluoro acids (78–90% ee) and β-fluoro alcohols (89–>95%ee) of well defined stereochemistry are prepared via the diastereoselective fluorination of chiral imide enolates with NFOBS (3).

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