Effects of salivary gland active principle (Parotin (cas 1392-81-0)) on glycaemic level and hepatic glycogen content in alloxan-diabetic rats: Salivary gland active principle and diabetic rats
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Add time:09/04/2019 Source:sciencedirect.com
The diabetic young rats, after a single dose of 0.30 mg/100 g of body weight of parotin returned to glycaemic levels near to normal. The hepatic glycogen of the same animals was increased compared to the controls. Two hypotheses were suggested: (a) parotin could act as a part of parotid gland secretion with an effect synergic to insulin; (b) parotin could act at a level of membrane receptors, facilitating the carriage of glucose and promoting the activities of rhythm of hepatic glycokinase synthesis.
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