Preparation, antimicrobial evaluation, and mutagenicity of [2-hydroxyaryl]-[1-methyl-5-nitro-1H-2-imidazolyl]methanols, [5-tert-Butyl-2-methylaminophenyl]-[1-methyl-5-nitro-1H-2-imidazolyl]methanol, and [2-Hydroxyaryl]-[1-methyl-5-nitro-1H-2-imidazolyl] ketones

Add time:07/15/2019    Source:sciencedirect.com

Efficient preparations of the titled compounds are described, their antimicrobial activity and mutagenic properties being evaluated. Some of the studied compounds are nonmutagenic and present a MIC as low as some of the usual standards in the field.

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