3-Urea-1-(phenylmethyl)-pyridones as novel, potent, and selective EP3 receptor antagonists
-
Add time:09/02/2019 Source:sciencedirect.com
A series of 3-urea-1-(phenylmethyl)-pyridones was discovered as novel EP3 antagonists via high-throughput screening and subsequent optimization. The synthesis, structure–activity relationships, and optimization of the initial hit that resulted in potent and selective EP3 receptor antagonists such as 11g are described.
We also recommend Trading Suppliers and Manufacturers of (+-)-5-Butoxy-1-(phenylmethyl)-2-pyrrolidinone (cas 136410-30-5). Pls Click Website Link as below: cas 136410-30-5 suppliers
Prev:ReviewFragrance material review on carbonic acid, methyl phenylmethyl ester
Next:Regioselectivity of the ring opening in the reaction of phenyloxirane, (phenylmethyl)oxirane and (2-phenylethyl)oxirane with K−, K+(15-crown-5)2) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- A novel synthesis of 2,5-diaryl-3-(phenylmethyl)thiophenes09/06/2019
- Synthesis of (2S,5S)-2,5-bis(phenylmethyl)-1,4-diazabicyclo[2.2.2]octane09/05/2019
- Enhancement of the behavioral effects of endogenous and exogenous cannabinoid agonists by phenylmethyl sulfonyl fluoride09/04/2019
- Regioselectivity of the ring opening in the reaction of phenyloxirane, (phenylmethyl)oxirane and (2-phenylethyl)oxirane with K−, K+(15-crown-5)209/03/2019
- ReviewFragrance material review on carbonic acid, methyl phenylmethyl ester09/01/2019
