N-Substituted 2-Amino-4-pentenoic Acids for Amino Acid Protection and Resolution

Add time:09/02/2019    Source:sciencedirect.com

N-Substituted 2-amino-4-pentenoic acid derivatives employed for the protection of racemic amino acids were shown to be capable of permitting the chromatographic separation of R and S isomers. When Nα was disubstituted with benzyl and phenylfluorenyl groups, the racemic amino acids could be separated with facility on open silica gel columns. Further, the optically pure N-protected amino acids so derived could be used for the preparation of misacylated suppressor transfer RNAs.

We also recommend Trading Suppliers and Manufacturers of 2-Pentenoic acid, 3-Methyl-, ethyl ester (cas 15676-99-0). Pls Click Website Link as below: cas 15676-99-0 suppliers

Prev:Short communicationThe mechanistic promiscuity of the enzymatic esterification of chiral carboxylic acids
Next:Cascade synthesis of the first imidazo[4,5-e]-thiazolo[2,3-c][1,2,4]triazine derivative)