Short sequence-paperSequence of a putative transporter from rabbit kidney related to the Na+/glucose cotransporter gene family☆
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Add time:09/05/2019 Source:sciencedirect.com
A 2 kb cDNA, RK-D, was isolated from a rabbit renal library by hybridization with the Na+/glucose cotransporter (SGLT1) cDNA. The mRNA for RK-D is also approximately 2 kb and is found predominantly in kidney. The RK-D cDNA encodes a protein of 597 amino acids related in sequence to the SGLT family of sodium-coupled transporters, all of which are related to the Na+/glucose cotransporter, SGLT1. Because of the high sequence similarity and conservation of ‘signature’ family features, it is very likely that RK-D encodes a Na+-dependent cotransporter.
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