An axial t-butyl group: Crystal structure of 1-phenyl-c-4-t-butyl-r-cyclohexylpiperidine hydrochloride

Add time:09/03/2019    Source:sciencedirect.com

The structure of 1-Phenyl-c-4-t-butyl-r-cyclohexylpiperidine hydrochloride 1 is shown by X-ray crystallography to have an axial t-butyl group. The conformational deformations. are smaller than expected except for the outward bending of the alkyl substituent with a concomittant flattening of the corresponding half part of the chair.

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