Synthesis of (3α,7β,17α)-7-methyl-19-norpregn-5(10)-en-20-yne-3,7,17-triol, a metabolite of ORG OD14, and its 7-epimer

Add time:09/02/2019    Source:sciencedirect.com

The syntheses of the 7β-hydroxy metabolite of ORG OD14 (Livial®), (3α,7β,17α)-7-methyl-19-norpregn-5(10)-en-20-yne-3,7,17-triol (35), and its 7-epimer, (3α,7α,17α)-7-methyl-19-norpregn-5(10)-en-20-yne-3,7,17-triol (11), are described.

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