A revised method for the synthesis of 1,1-Bis(4-hydroxyphenyl)-2-phenylethylene (BHPE) and its derivatives

Add time:09/02/2019    Source:sciencedirect.com

The synthesis of 1,1-bis(4-hydroxyphenyl)-2-phenylethylene, which is of biological interest, has been reported by several authors in the past. In this article an improved method is introduced. Also a protective group which is easily attached and removed is used. This procedure provides milder reaction conditions and better yields while the number of steps involved in the synthesis are reduced. Furthermore the reactions are clean and formation of by-products which lead to poorer yields are avoided.

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