Introduction of a benzoyl group onto riboside in aqueous solution: One-step synthesis of 6-chloropurine 2′,3′-di-O-benzoylriboside

Add time:09/06/2019    Source:sciencedirect.com

A benzoyl group was introduced onto the 3′-hydroxyl group of 6-chloropurine riboside by treatment with benzoylating agents in the presence of an organic or inorganic base in aqueous solution, in which further reaction gave 6-chloropurine 2′,3′-di-O-benzoylriboside.

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