Helical primary structures of four-membered rings: (M)-trispiro[3.0.0.3.2.2]tridecane☆

Add time:09/03/2019    Source:sciencedirect.com

The synthesis of (M)-trispiro[3.0.0.3.2.2]tridecane [(M)-4], the first hydrocarbon with a helical primary structure of four-membered rings, is described. Key step is the kinetic resolution of a cyclobutanone through reduction with bakers' yeast. As compared to its analogue of three-membered rings, (M)-trispiro[2.0.0.2.1.1]nonane [(M)-1], the specific rotation of (M)-4 is cut in three. According to molecular mechanics calculations this could be due to a potential to adopt different conformations, not given in (M)-1, and to the fact, that (M)-4 describes a distinctly shorter section of a helix than (M)-1.

We also recommend Trading Suppliers and Manufacturers of Tridecane, 3-methylene- (cas 19780-34-8). Pls Click Website Link as below: cas 19780-34-8 suppliers

Prev:Critical micelle concentration of tridecane, tetradecane and hexadecane phosphonic acids and their mono- and disodium salts
Next:Theoretical study of tetracyclo[3.3.3.13,10.17,10]tridecane (bowlane) and its methylene spacer edge and lip expanded (−CH2−)n(n = 1–4) homologs)