Gramine (cas 87-52-5) inhibits angiogenesis and induces apoptosis via modulation of TGF-β signalling in 7,12 dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinoma
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Add time:07/16/2019 Source:sciencedirect.com
BackgroundTransforming growth factor-β (TGF-β) and its receptors are considered as a novel target in cancer chemotherapy. Gramine (cas 87-52-5), an indole alkaloid, possesses various pharmacological properties including antiproliferative and anticancer. However, the anti-angiogenic property remains unexplored.
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