Stereoselective synthesis of allyl- and homoallylglycines

Add time:09/03/2019    Source:sciencedirect.com

A new method for the synthesis of N-protected allyl- and homoallylglycines was developed from aspartic and glutamic acid derivatives. The carboxylic side-chains of aspartic and glutamic derivatives was first transformed into the Weinreb amide by coupling with N,O-dimethylhydroxylamine and then reduced into the corresponding aldehyde. The latter could react with methyl-triphenylphosphonium bromide to yield the title compounds with 50% total yield.

We also recommend Trading Suppliers and Manufacturers of Allyl triphenylphosphonium chloride (cas 18480-23-4). Pls Click Website Link as below: cas 18480-23-4 suppliers

Prev:Studies on the separation and in-situ sintering solidification of strontium by a highly-efficient titanate-based adsorbent
Next:The tandem insertion of allyl carbenoids and aldehydes or ketones into zirconacyclopentanes: Variation of the allyl Moiety and functionalisation of the final carbon-zirconium bond)