Chapter 4 - Acetylenic Epoxy Fatty Acids: Chemistry, Synthesis and Their Pharmaceutical Applications

Add time:09/03/2019    Source:sciencedirect.com

Currently, about 50 natural epoxy acetylenic fatty acids are known. This chapter describes biologically active epoxy acetylenic fatty acids and related compounds isolated from different sources. Intensive searches for new class of pharmacologically potent agents produced by living organisms have resulted in the discovery of dozens of such compounds possessing anticancer, cytotoxic, antibacterial, antiviral, and other activities. Mainly, acetylenic epoxides belong to a class of molecules containing triple bond(s) and epoxy group(s) belonging to different lipid classes and/or other groups. This chapter emphasizes the role of natural and synthetic acetylenic epoxides and other related compounds as an important source for drug discovery.

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