Comprehensive behavioral study of the effects of Vanillin (cas 121-33-5) inhalation in mice

Add time:09/04/2019    Source:sciencedirect.com

Vanillin (cas 121-33-5) is widely used in food and cosmetics, among other substances, for its sweet smell. However, the neuropsychological effects of vanillin inhalation have not been elucidated. In this study, we investigated the effect of vanillin inhalation on mouse behavior. First, we investigated whether the aroma of vanillin was attractive or repulsive for mice. Thereafter, the mice inhaled vanillin for 20 min before each test in a series of behavioral tests (elevated plus maze, open field, Y-maze, tail suspension, cotton bud biting, and Porsolt forced swim tests). In these tests, the mice showed a neutral response to vanillin. Mice that inhaled vanillin had a suppressed pain response in the hot plate test. In addition, the grip strength of the forelimbs of mice that inhaled vanillin was decreased. No significant differences were found between the mice inhaling vanillin and control mice in the open field, Y-maze, tail suspension, forced swimming, and aggression tests. These results show that vanillin inhalation has anti-nociceptive effects, similar to other routes of administration. The results also show that vanillin inhalation does not cause significant behavioral effects.

We also recommend Trading Suppliers and Manufacturers of Vanillin (cas 121-33-5). Pls Click Website Link as below: cas 121-33-5 suppliers

Prev:Full Length ArticleInhibitory effects of furfural and vanillin on two-stage gaseous biofuel fermentation
Next:Salting-out effects on Vanillin (cas 121-33-5) extraction by supercritical carbon dioxide from aqueous Vanillin (cas 121-33-5) solution containing salts)