Expedient synthesis of 3-substituted-1,2,3,6-tetrahydropyridines
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Add time:09/08/2019 Source:sciencedirect.com
The treatment of alkyl or aryl halides with an excess of tetrakis(pyridine)lithium tetrakis(N-dihydropyridyl)aluminate affords the corresponding 3-substituted-1,2,3,6-tetrahydropyridines in moderate to good yields via a tandem alkylation–reduction reaction.
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