An in vitro evaluation of anti-aging effect of guluronic acid (cas 15769-56-9) (G2013) based on enzymatic oxidative stress gene expression using healthy individuals PBMCs

Add time:09/25/2019    Source:sciencedirect.com

BackgroundAging is usually associated with increased levels of oxidants, and may result in damages caused by oxidative stress. There is a direct relationship between aging and increased incidence of inflammatory diseases. The present research intended to study the anti-aging and anti-inflammatory effects of the drug G2013 (guluronic acid (cas 15769-56-9)) at low and high doses on the genes expression of a number of enzymes involved in oxidative stress (including SOD2, GPX1, CAT, GST, iNOS, and MPO) in peripheral blood mononuclear cells (PBMCs) of healthy individuals under in vitro conditions.

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