Synthesis of pyrrolidine analogues of solamin

Add time:09/06/2019    Source:sciencedirect.com

A convergent synthesis of pyrrolidine analogues of solamin, which possessed a pyrrolidine in place of the tetrahydrofuran ring, was presented in a facile route from 2,5-trans-bis(methoxycarbonyl)pyrrolidine. The stereochemistry of pyrrolidine core unit was determined by 1H NMR spectroscopic analysis.

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