4.01 - Pyrazoles

Add time:09/05/2019    Source:sciencedirect.com

Five-membered ring systems containing two nitrogen atoms adjacent to each other are called pyrazoles. This chapter serves to cover the extensive literature on pyrazoles during the 10 year period, 1996–2006. The previous two chapters of this series, on pyrazoles, dealt more with the theoretical, experimental structural, and thermodynamic methods and less with the reactivity, synthesis, and applications of pyrazoles. During the last 10 years, more literature has appeared on the synthesis and reactivity of pyrazole-fused ring systems. Furthermore, the medicinal chemistry applications of pyrazoles and fused ring systems have found numerous applications in drug discovery. Also, pyrazoles have been utilized as reagents in synthesis. This chapter focuses on these current developments.

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