On the reaction of carboxylic acids and isonitriles with conventional heating

Add time:09/06/2019    Source:sciencedirect.com

Control over the formation of N-formylamides versus the formation of captodative alkenes from the reaction of arylacetic acids with isonitriles has been achieved. Low temperatures and high concentrations favor alkenes, and high temperatures and low concentrations favor N-formylamides.

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