A one-pot three-component synthesis of dithiocarbamates starting from vinyl pyridines and vinyl pyrazine under solvent- and catalyst-free conditions

Add time:09/09/2019    Source:sciencedirect.com

A novel and efficient one-pot three-component reaction for the synthesis of dithiocarbamates at room temperature under solvent- and catalyst-free conditions, starting from readily available amines, CS2 and vinyl pyridines and vinyl pyrazine is reported. Excellent yield, green reaction conditions, and complete regioselectivity toward anti-Markovnikov adducts are particular advantages of this work.

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