Original articleSynthesis, characterization and anticancer activity of gold(I) complexes that contain Tri-tert-butylphosphine (cas 13716-12-6) and dialkyl dithiocarbamate ligands
-
Add time:09/07/2019 Source:sciencedirect.com
Two new gold(I) complexes that contain tri-ter-butylphosphine and dialkyl dithiocarbamate ligands were synthesized and characterized by FTIR, NMR spectroscopy, Cyclic voltammetry, elemental analysis and X-ray diffraction. The in vitro cytotoxicity of both complexes was examined against A549 (lung cancer), MCF7 (breast cancer), and HeLa (cervical cancer) human cancer cell lines. Both complexes exhibit very strong in vitro cytotoxic effects against A549, MCF7 and HeLa cell lines. The screening of the cytotoxic activity based on IC50 data against the A549, MCF7, and HeLa lines shows that the synthesized gold(I) complexes are highly effective, particularly against HeLa cancer cell line. Based on IC50 data, the cytotoxic activity of both complexes is better than well-known commercial anticancer drug cisplatin against all the three cancer lines tested.
We also recommend Trading Suppliers and Manufacturers of Tri-tert-butylphosphine (cas 13716-12-6). Pls Click Website Link as below: cas 13716-12-6 suppliers
Prev:The effects of DHEA, 3β-hydroxy-5α-Androstane-6,17-dione (cas 13713-89-8), and 7-amino-DHEA analogues on short term and long term memory in the mouse
Next:Synthesis, structures and spectroscopic properties of cyclometalated Tri-tert-butylphosphine (cas 13716-12-6) complexes of platinum(II)) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
-
Health and Chemical more >
-
Related Products