Peritoneal dialysis for severe methyprylon (cas 125-64-4) intoxication

Add time:09/09/2019    Source:sciencedirect.com

The appropriate therapy for methyprylon (cas 125-64-4) (Noludar) poisoning has remained controversial, owing to a lack of reliable pharmacologic data concerning the most effective way to remove the drug after a large ingestion. We recently employed peritoneal dialysis to treat a 16-year-old girl, who had ingested 6.3 gm of methyprylon, and were able to recover more than 80% of the unmetabolized drug in the dialysate. Clinical recovery was complete within eight hours. This appears to be a safe and effective method to remove the drug in the child or adult with a serious intoxication.

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