Total synthesis of panaxytriol and Panaxydiol (cas 708257-91-4)

Add time:07/15/2019    Source:sciencedirect.com

The enantioselective total synthesis of the diyne containing natural products panaxytriol and (3S,10R)-panaxydiol from l-tartaric acid is reported. Key steps in the synthesis include the elaboration of a γ-hydroxy amide derived from tartaric acid to the required alkyne and the formation of the desired diyne unit by a Cadiot–Chodkiewicz coupling.

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