Asymmetric synthesis of (R)-(+)-etomoxir via enzymatic resolution

Add time:07/11/2019    Source:sciencedirect.com

An asymmetric synthesis of (R)-(+)-etomoxir 3, employing enzymatic resolution of ethyl 2-alkyl-2,3-dihydroxypropionate using Amano AK via transacylation is reported.

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